Deaths preventable in the US by improvements in use of clinical preventive services

From:
ProCor
Date:
27 July 2010
Increasing provision of clinical preventive services (up to 70% of those requiring the intervention) could lead to dramatic number of deaths prevented...

Title: Deaths preventable in the US by improvements in use of clinical preventive services

Authors: T Farley, M Dalal, F Mostashari, T Frieden

Reference: Am J Prev Med 2010; 38(6): 600-609
http://www.ncbi.nlm.nih.gov/pubmed/20494236

Reviewer: Joaquin Barnoya, MD, MPH, Contributing Editor, ProCor; Research Assistant, Professor of Surgery, Washington University in St. Louis, Missouri, USA; Director, Research and Education, Unidad de Cirugia Cardiovascular de Guatemala, Guatemala

Reviewer comments: As usual, preventive services are underutilized. However, this paper shows how increasing provision of preventive services (up to 70% of those requiring the intervention) could lead to dramatic number of deaths prevented. The deaths prevented from smoking cessation are not as high as one would expect but this is due to the fact that smoking prevalence in the US has decreased significantly in the last twenty years. Countries with different risk factors prevalence (e.g., China with a 50% smoking prevalence among males) might yield different number of deaths prevented from each clinical preventive service.

Purpose of study: To estimate the number of deaths that could be prevented by increasing the utilization of nine clinical preventive services in the US population.

Location of study: United States

Methods: Clinical preventive services that have been given the highest level (Grade A) of recommendation from the United States Preventive Services Task Force and known to prevent cardiovascular disease were evaluated. The Task Force recommendations regarding screening for modifiable risk factors for disease, the effects of successful risk factor modification was modeled by the population risk. Among the interventions modeled are: identification and treatment of hypertension and elevated LDL cholesterol, aspirin for people at elevated risk of CVD, and smoking cessation. The model is based on the prevalence of risk factors for which interventions are recommended, the effect of those risk factors on mortality, the effect of the interventions on mortality in those at risk, and current and achievable rates of utilization of the interventions. The 2007 US population of adults (ages 25-79 years) is used for the analysis.

Results: Treatment of hypertension (70% of those requiring treatment) had the potential to prevent the most deaths (28,000) followed by treatment of hyperlipidemia (15,000) and aspirin prophylaxis (9000). Every 10% increase in hypertension treatment would lead to an additional 14,000 deaths prevented per year in those aged 80 years and younger. Smoking cessation would lead to an additional 7000 deaths prevented per year for each 5% increase (it could prevent a larger number if cessation rates would be easier to attain). Cancer screening recommendations were predicted to have lower potential.

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