Smoking and risk of myocardial infarction in women and men
The risks associated with smoking were consistently higher in women than in men. This difference persisted after adjustment for other risk factors. Women may be more sensitive than men to cardiovascular harmful effects of smoking...
Patients with nonvalvular atrial fibrillation at low risk of stroke during treatment with aspirin
Treatment of atrial fibrillation with aspirin reduces the risk for stroke, less effectively than warfarin, but could be an attractive modality for those at low risk for stroke....
High-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary edema
This study compared high dose isosorbide dinitrate plus standard dose furosemide to high dose furosemide plus a low dose infusion of isosorbide for the treatment of acute pulmonary edema. The authors found a significant reduction in the need for intubation and in the rate of myocardial infarction in the high dose nitrates group...
Prevention of heart failure by antihypertensive drug treatment
This study demonstrates that diuretic based stepped-care is effective in prevention of the development of heart failure in the older patients with isolated systolic hypertension. Heart failure risk was reduced by approximately 50%...
Losartan versus Captopril in patients over 65 with heart failure
This study investigates the effect of an angiotensin II type 1 receptor antagonist, losartan, versus the ACEI captopril in the setting of CHF in an elderly patient population...
Comparison of hydrocholorothiazide, atenolol, nitrendipine, and enalapril in antihypertensive treatment
In this study to evaluate the effectiveness and tolerability of four different antihypertensive drugs, atenolol continued, after 48 weeks, to have the best response and tolerability rate of 48% compared to enalapril (42.7%), HCTZ (35.4%), and Nitrendipine (32.9%).
Fish consumption and the 30-year risk of fatal myocardial infarction
There is a significant inverse association between fish consumption and the 30-year risk of death from coronary heart disease, particularly nonsudden death from myocardial infarction. There was a 42% and 67% relative risk reduction for MI deaths and nonsudden death respectively in the groups consuming 35 g/day of fish compared to the non-fish eaters...
Alcohol consumption and risk of a major coronary event
This study found a significant reduction in risk of CAD events for men who took one to four alcoholic drinks daily on five or six days per week and for women who took one or two drinks daily over the same period...
Mortality attributable to cigarette smoking in China
China is the largest tobacco producing and consuming country in the world. This prospective cohort of 1696 Chinese people followed for a mean of 19 years describes the mortality risk associated with smoking...
Passive smoking and coronary heart disease
In non-smoking women, regular exposure to secondhand smoke at home or work may increase the risk of CHD...
Reduced cardiovascular mortality risk in smokers who are physically active
Vigorous physical activity in smokers was associated with an almost 40% lower cardiovascular mortality. CV mortality in physically active smokers was only slightly higher than it was in active non-smokers...
First heart attack in patients of Indian subcontinent and European origin
Migrants to the United Kingdom from the Indian subcontinent have a higher mortality from coronary heart disease than the indigenous population. Studies have shown conflicting results regarding the post MI outcome of Indian and European origin patients...
Cardiac procedures and outcomes in elderly patients with myocardial infarction
One-year mortality rates for elderly patients with myocardial infarction were similar in the US and Ontario in 1991. This study suggests that the greater use of revascularization procedures in the US does not improve the long-term survival rates of elderly patients with acute MI...
Birth weight and CVD risk in women
Birth weight was inversely related to the incidence of non-fatal coronary heart disease and stroke. Relative risk for women with birth weights less than 5 lb. was 1.49 compared to women with birth weights between 7 and 8.5 lb...
Low job control and CHD risk
This study provides evidence for an increase in risk of developing new CHD among workers with low job control compared to workers with high job control. Job control was defined as the employees' ability to have authority and choice in planning, schedule, speed and variety of their labor...
Effect of socioeconomic status on heart attack and coronary death
The importance of primary and secondary prevention in the most deprived communities holds greater promise for improving public health than advances in high-technology hospital care...
Prevalence of hypertension in seven populations of West African origin
The basis for the increased prevalence of hypertension with age among persons of African descent remains undefined. Some argue for a genetic basis while others look to environmental factors.This study lends support to the influence of environmental factors over genetic predisposition in determining the gradient of hypertension across these populations...
Effect of digoxin on mortality and morbidity in patients with heart failure
The efficacy of digoxin, particularly its effect on mortality, in patients with congestive heart failure in normal sinus rhythm has been debated for years. The authors of this study conclude that, in clinical practice, digoxin is likely to affect the frequency of hospitalization, but not survival...
Comparative study of hypertension prevalence, awareness, treatment, and control rates in the Caribbean
In the Caribbean, the epidemiological transition has led to an increased prevalence of hypertension, a key risk factor for cardiovascular disease which represents the most common cause of death among adults in the region. This study compares the hypertension situation in Jamaica, Barbados, and St. Lucia...
Blood pressure and atherogenic lipoprotein profiles of fish-diet and vegetarian villagers in Tanzania
In a comparative study of two ethnically identical groups in Tanzania, one on a fish diet and the other on a vegetarian diet, the fish-consuming group had lower values of systolic and diastolic blood pressure as well as plasma lipids...
