Maternal diabetes and obesity may have lifelong impact on health of offspring
The study conducted in Canada addresses the impact of the growing obesity and diabetes epidemics on pregnant women and their offspring... Journal Summary
Community-Based screening for cardiovascular disease and diabetes using HbA1c
Among individuals without a prior diagnosis of diabetes, 1 in 5 persons had HbA1c levels considered to be at high-risk for diabetes, and 3.4% had HbA1c levels indicating the presence of diabetes. Positive associations were found between levels of HbA1c and glucose measurements with advancing age, higher blood pressure, BMI, total cholesterol... Journal Review
Obesity and the metabolic syndrome in children and adolescents
The metabolic syndrome is clearly not limited to adults, and appears to be highly prevalent among obese children and adolescents. Obese children also exhibited trends toward impaired glucose tolerance, insulin resistance, high blood pressure, and elevated serum lipids level... Journal Review
Metabolic syndrome: Prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
The prevalence of the metabolic syndrome was nearly one quarter in men and in women. The prevalence of the metabolic syndrome was related to race, particularly in men. Prevalence was also related to increasing age and body mass index... Journal Review
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
In 2001, the prevalence of self-reported obesity among US adults increased from 20% in 2000 to 21% in 2001. The prevalence of diabetes increased from approximately 7% in 2000 to nearly 8% in 2001. Rates was affected by ethnicity and location... Journal Review
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women
The risk of developing diabetes increased with the number of hours spent watching television per week. However, the study suggests that the risk of diabetes associated with television watching was at least partially because of obesity... Journal Review
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
This study clearly demonstrates that a multifactorial strategy reduces the risk of cardiovascular disease among patients with type 2 diabetes. Patients underwent implementation of behavior modification and pharmacologic therapy targeting hyperglycemia, hypertension, dyslipidemia, and microalbuminuria; treatment also included a dietary intervention, physical activity, and smoking cessation... Journal Review
Metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
Increased glucose and serum insulin levels (but not dyslipidemia) were associated with increased mortality from CVD and all causes. Participants in this study who exhibited the metabolic syndrome were 2.9 times more likely to die of CHD... Journal Review
Nut and peanut butter consumption and risk of type 2 diabetes in women
Two studies on healthy diets: one on the benefits of higher nut intake for lowering risk of type 2 diabetes in women; and one on the effect of diet on risk of coronary heart disease... Journal Review
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
Diabetes risk can be significantly lowered in both men and women with impaired glucose tolerance who are given detailed advice and information about how to lead a healthier lifestyle in regards to diet and physical activity... Journal Review
Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect
This is the first study to demonstrate a reduced risk for developing diabetes mellitus with a lipid-lowering medication such as pravastatin. The effects of prevastatin that contribute to this reduction include triglyceride lowering, anti-inflammatory effects, and the effect on endothelial function... Journal Review
Global burden of diabetes
The global prevalence of diabetes in adults was estimated to be 4% in 1995, and was projected to rise to 5.4% by the year 2025. The number of adults with diabetes is estimated to rise from 135 million in 1995 to 300 million in the year 2025... Journal Review
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
Fatality rate for first myocardial infarction is higher in diabetic than nondiabetic patients (45% men and 39% in women with diabetes, 38% men and 25% in women without diabetes). This population would not have the chance to benefit from secondary prevention therapies, indicating that aggressive risk factor reduction should be offered to prevent the first myocardial infarction... Journal Review
Intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus
The authors of this study have already demonstrated a 30% reduction in one-year mortality among this group of patients randomized to intensive insulin therapy. In this report, they extend patient follow-up to 3.4 years... Journal Review
